A bunch of 10 Turkish scientists working in 5 totally different organizations in Malatya and Izmir has developed a brand new technological product for the analysis of familial Mediterranean fever (FMF), marking a big growth in drugs.
The growth goals to assist sufferers with this genetic illness, because the newly developed technique will scale back the analysis time to solely half-hour.
The Izmir Biomedicine and Genome Center, with the assist of the Scientific and Technological Research Council of Turkey (TÜBİTAK), shared particulars of the patent utility on Monday, which is predicted to be the primary technique ever used to shortly diagnose the illness nationally and internationally.
Familial Mediterranean fever is an inherited situation characterised by recurrent episodes of painful irritation within the stomach, chest or joints. It is a extreme illness that often happens in childhood or in the course of the teenage years. However, generally, the preliminary signs seem later in life.
Highlighting that the research is totally domestically run, professor Dr. Ceyhun Açarı from Malatya’s Inönü University mentioned: “FMF is one of the common genetic diseases in Türkiye. However, it’s still quite hard to diagnose the disease.”
Sharing the difficulties within the analysis of the illness as the method often takes three to 4 months, Açarı famous that the extended procedures could result in kidney failure in sufferers.
“Considering these hurdles at the diagnostic stage, we thought that a protein called pyrin could be used in the diagnosis,” Açarı, who can be the lecturer on the Pediatrics Department of Pediatric Rheumatology, defined.
“The newly developed method can be accurate for over 90% of patients who remained undiagnosed for years,” he identified.
The research will proceed with totally different initiatives on a bigger scale. The moveable sensor gadget designed within the venture has a “high potential to be used in hospitals and later be placed in the market for commercial use,” the professor added.
Meanwhile, one other physician related to the venture, Idil Karaca Açarı, emphasised that the venture’s intention is to develop an alternate new diagnostic technique after figuring out the basis reason behind the illness.
“After we developed our project intellectually, we quickly headed to the writing stages of the project. During the writing phase, we created the entire project team and work packages. Later, we presented them to TÜBITAK. After the project was approved, we actively started the experimental phases of the project,” she defined.
Açarı famous that the venture was developed with the joint efforts of 5 totally different establishments, together with 4 universities and a world analysis heart. Turgut Özal University in Malatya, Inönü University, the International Biomedicine and Genome Center in Izmir, Dokuz Eylül University and Izmir Katip Çelebi University participated within the app growth, she added.
Optical sensor methods
“The goal was to develop an alternative new diagnostic method for FMF. For this, we used optical sensor systems,” the professor mentioned.
“Dr. Süleyman Köytepe was the one working on multi-functional chemical surface modifications so that optical sensor systems can measure different chemical processes. Meanwhile, professor Dr. Burhan Ateş conveyed the active scientific follow-up of the syntheses on antibody and antigen surface design,” Açarı added.
Stressing that the venture has yielded over 90% optimistic outcomes whereas learning sufferers’ samples, she defined that the affected person samples had been studied within the multidisciplinary venture and within the optical sensor methods thus contributing to the success of the venture.
With the event of this multidisciplinary venture, we now have found an alternate technique for the analysis of FMF, contributing to the worldwide and nationwide literature, the medical skilled mentioned, including: “We as a team are feeling immensely happy to make this development in the field of medicine,” she concluded.
